Tumour-Initiating cells: The cell that rocks the tumour
Nature Reviews Cancer 17, 3 (2017).
doi:10.1038/nrc.2016.149
Author: M. Teresa Villanueva
Latil et al. have shown that the cell of origin of squamous cell carcinomas (SCCs) controls epithelial-to-mesenchymal transition (EMT) and aggressiveness of these tumours. SCCs derived from hair follicles are much more prone to undergo EMT and have more metastatic potential compared with SCCs
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: M. Teresa Villanueva Tags: Research Highlight Source Type: research