Post-transcriptional gene regulation by mRNA modifications

Nature Reviews Molecular Cell Biology 18, 31 (2017). doi:10.1038/nrm.2016.132 Authors: Boxuan Simen Zhao, Ian A. Roundtree & Chuan He The recent discovery of reversible mRNA methylation has opened a new realm of post-transcriptional gene regulation in eukaryotes. The identification and functional characterization of proteins that specifically recognize RNA N6-methyladenosine (m6A) unveiled it as a modification that cells utilize to accelerate
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research