Alternative polyadenylation of mRNA precursors

Nature Reviews Molecular Cell Biology 18, 18 (2017). doi:10.1038/nrm.2016.116 Authors: Bin Tian & James L. Manley Alternative polyadenylation (APA) is an RNA-processing mechanism that generates distinct 3′ termini on mRNAs and other RNA polymerase II transcripts. It is widespread across all eukaryotic species and is recognized as a major mechanism of gene regulation. APA exhibits tissue specificity and is important for
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research