Reverse-topology membrane scission by the ESCRT proteins

Nature Reviews Molecular Cell Biology 18, 5 (2017). doi:10.1038/nrm.2016.121 Authors: Johannes Schöneberg, Il-Hyung Lee, Janet H. Iwasa & James H. Hurley The narrow membrane necks formed during viral, exosomal and intra-endosomal budding from membranes, as well as during cytokinesis and related processes, have interiors that are contiguous with the cytosol. Severing these necks involves action from the opposite face of the membrane as occurs during the
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research