Biochemical and functional analysis of COS3A, a novel CD63-specific monoclonal antibody

Conclusions:The mAbCOS3A recognized the CD63 molecule and strongly diminished phagocytosis of bacteria by granulocytes, suggesting that CD63 may play a crucial role in the initial step of phagocytosis. MAb COS3A is therefore suitable for both biochemical and functional studies of CD63, and may be used for further study of the mechanism of phagocytosis and also in therapeutic approaches. DOI 10.12932/AP0735
Source: Asian Pacific Journal of Allergy and Immunology - Category: Allergy & Immunology Source Type: research