Transcatheter closure of perimembranous ventricular septal defects (VSDs) using the Amplatzer duct occluder I device

Isolated ventricular septal defects (VSDs) are the commonest congenital cardiac malformation. Approximately 80% of clinically relevant defects are perimembranous (pm VSD) [1]. Device closure of muscular and perimembranous VSD appears to offer a real alternative to the standard surgical approach [2]. However, the initial enthusiasm for transcatheter closure of clinically relevant pmVSDs was hampered with the anatomical challenges and the reported high rate of early and late heart block. Muscular defects are more amenable to closure, being distant from important structure.

Source: Progress in Pediatric Cardiology - December 15, 2016 Category: Cardiology Authors: R. Sobhy, A El-Sisi, AM Fattouh, HM Agha, SA El-Saiedi, W Attia, DM Abdelaziz, H Hamza Source Type: research