Clinical Manifestations and Molecular Characterization of Pertactin-Deficient and Pertactin-Producing Bordetella pertussis in Children, Philadelphia 2007-2014

Conclusions. In this cohort of predominantly unimmunized infants, clinical disease did not differ between infection with pertactin-deficient and those with pertactin-producing B. pertussis. Molecular analyses demonstrated remarkable PFGE strain diversity, with multiple mechanisms and molecular sites of pertactin inactivation.

Source: Clinical Infectious Diseases - December 15, 2016 Category: Infectious Diseases Authors: Vodzak, J., Queenan, A. M., Souder, E., Evangelista, A. T., Long, S. S. Tags: ARTICLES AND COMMENTARIES Source Type: research