Neurodegenerative disease: Probing prions

Nature Reviews Neuroscience 18, 5 (2017). doi:10.1038/nrn.2016.174 Author: Katherine Whalley It has been hypothesized that the spread of misfolded proteins underlies patterns of neurodegeneration. Using a highly sensitive detection method, Alibhai et al. observed widespread early distribution of prion protein 'seeds' in a mouse model of prion disease but no correlation between the regions
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research