Integration of expression quantitative trait loci and pleiotropy identifies novel psoriasis susceptibility gene, PTPN1

ConclusionsThe results highlight the eQTL enrichment and pleiotropy in psoriasis and schizophrenia, suggest a possible key role of the PTPN1 gene in the etiology of psoriasis.

Source: The Journal of Gene Medicine - September 30, 2016 Category: Genetics & Stem Cells Authors: Xianyong Yin, Yuan Lin, Changbing Shen, Ling Wang, Xianbo Zuo, Xiaodong Zheng, Sen Yang, Jianjun Liu, Kirk C. Wilhelmsen, Xuejun Zhang Tags: RESEARCH ARTICLE Source Type: research