MicroRNAs in Lung Development and Disease

MicroRNAs (miRNAs) are small ( ∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in pediatric respiratory disease, incl uding cystic fibrosis, asthma, and bronchopulmonary dysplasia.

Source: Paediatric Respiratory Reviews - December 13, 2016 Category: Respiratory Medicine Authors: Dustin Ameis, Naghmeh Khoshgoo, Barbara M. Iwasiow, Phillip Snarr, Richard Keijzer Source Type: research