MCT8 deficiency in Purkinje cells disrupts embryonic chicken cerebellar development
In conclusion, early MCT8 deficiency in Purkinje cells results in both cell-autonomous and non-autonomous effects on cerebellar development and indicates that MCT8 expression is essential from very early stages of development, providing a novel insight into the ontogenesis of the Allan–Herndon–Dudley syndrome.
Source: Journal of Endocrinology - Category: Endocrinology Authors: Delbaere, J., Vancamp, P., Van Herck, S. L. J., Bourgeois, N. M. A., Green, M. J., Wingate, R. J. T., Darras, V. M. Tags: Research Source Type: research