Cognitive sequelae of methanol poisoning involve executive dysfunction and memory impairment in cross-sectional and long-term perspective

Methanol poisoning leads to lesions in the basal ganglia and subcortical white matter, as well as to demyelination and atrophy of the optic nerve. However, information regarding cognitive deficits in a large methanol sample is lacking. The principal aim of the present study was to identify the cognitive sequelae of methanol poisoning and their morphological correlates. A sample of 50 patients (METH; age 48  ± 13), 3–8 months after methanol poisoning and 57 control subjects (CS; age 49 ± 13) were administered a neuropsychological battery, 46 patients were followed in two years perspective.

Source: Alcohol - December 11, 2016 Category: Addiction Authors: O. Bezdicek, J. Michalec, M. Vaneckova, J. Klempir, I. Liskova, Z. Seidl, B. Janikova, M. Miovsky, J. Hubacek, P. Diblik, P. Kuthan, A. Pilin, I. Kurcova, Z. Fenclova, V. Petrik, T. Navratil, D. Pelclova, S. Zakharov, E. Ruzicka Source Type: research