Non-syndromic severe hypodontia caused by a novel frameshift insertion mutation in the homeobox of the MSX1 gene

Tooth agenesis is one of the most common craniofacial anomalies seen in human populations, characterized by the developmental absence of one or more teeth. For clinicians this type of anomaly can constitute a challenging clinical problem in many cases. Different terms have been used to describe missing primary and permanent teeth. Hypodontia is used to describe absence of less than six teeth excluding the third molar. An absence of more than six teeth excluding the third molar is termed oligodontia.

Source: Archives of Oral Biology - December 5, 2016 Category: Dentistry Authors: Mushriq F. Abid, M.A. Simpson, Christos Petridis, M.T. Cobourne, P.T. Sharpe Tags: Short communication Source Type: research