Synthesis and evaluation of a 99mTc tricarbonyl-labeled somatostatin receptor-targeting antagonist peptide for imaging of neuroendocrine tumors

A somatostatin receptor (SSTR)-targeting antagonist peptide (sst2-ANT) was radiolabeled with 99mTc tricarbonyl via a tridentate [N,S,N]-type ligand (L) to develop a radiodiagnostic agent, 99mTcL-sst2-ANT, for imaging of SSTR-expressing neuroendocrine tumors.

Source: Nuclear Medicine and Biology - December 8, 2016 Category: Nuclear Medicine Authors: Lauren Radford, Fabio Gallazzi, Lisa Watkinson, Terry Carmack, Ashley Berendzen, Michael R. Lewis, Silvia S. Jurisson, Dionysia Papagiannopoulou, Heather M. Hennkens Source Type: research