Single nucleotide polymorphisms of IFN{gamma} (+874 A/T) and IFN{gamma}R1 (-56 C/T) in Iranian patients with TB

Conclusions The cause of active TB in the patients seems to be due to the lack of effective IFN function or the lack of effective signaling connection between IFN and its receptor in presence of –56 C/T polymorphism in promoter region of IFNR1 gene.
Source: Transactions of the Royal Society of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Original Articles Source Type: research