The substrate of increased cortical FA in MS: A 7T post-mortem MRI and histopathology study
Conclusion:
FA increase was not due to lesional and non-lesional differences in microglia activation and/or proliferation. We found an increase in general cellular density without a notable difference in cellular size, that is, tissue compaction, as a possible alternative explanation.
Source: Multiple Sclerosis - Category: Neurology Authors: Jonkman, L. E., Klaver, R., Fleysher, L., Inglese, M., Geurts, J. J. Tags: Original Research Papers Source Type: research