Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults

Conclusions. In this cross-sectional analysis, LTI was associated with NCI, especially in those with higher CD4+ T-cell counts. Longitudinal studies to investigate the role of neuroinflammation and neuronal injury in LTI patients with NCI and trials of anti-Toxoplasma therapy should be pursued.

Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Bharti, A. R., McCutchan, A., Deutsch, R., Smith, D. M., Ellis, R. J., Cherner, M., Woods, S. P., Heaton, R. K., Grant, I., Letendre, S. L. Tags: HIV/AIDS Source Type: research