Protein export through the bacterial Sec pathway

Nature Reviews Microbiology 15, 21 (2017).
doi:10.1038/nrmicro.2016.161

Authors: Alexandra Tsirigotaki, Jozefien De Geyter, Nikolina Šoštaric´, Anastassios Economou & Spyridoula Karamanou
The general secretory (Sec) pathway comprises an essential, ubiquitous and universal export machinery for most proteins that integrate into, or translocate through, the plasma membrane. Sec exportome polypeptides are synthesized as pre-proteins that have cleavable signal peptides fused to the exported mature domains. Recent advances

Source: Nature Reviews Microbiology - November 27, 2016 Category: Microbiology Authors: Alexandra Tsirigotaki Jozefien De Geyter Nikolina Šoštaric´ Anastassios Economou Spyridoula Karamanou Tags: Review Source Type: research