Are recent statin recommendations to employ fixed doses and abandon targets effective for treatment of hypercholesterolaemia? Investigation based on number needed to treat
Conclusion
For optimum clinical effectiveness, initial LDL-C concentration must be considered in deciding whether a target will allow a greater decrease in LDL-C and thus a lower NNT than a fixed dose regimen. Individual variation in the LDL-C response to statins also makes post-treatment cholesterol measurement essential.
Source: European Journal of Preventive Cardiology - Category: Cardiology Authors: Soran, H., Adam, S., Durrington, P. N. Tags: Original scientific paper Source Type: research
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