Phxnlme: An R package that facilitates pharmacometric workflow of Phoenix NLME analyses

Pharmacometrics is a scientific discipline that integrates pharmacokinetics, pharmacodynamics, pharmacology, physiology, knowledge about diseases, and statistics to quantify interactions between drugs and patients using mathematical models [1 –3]. In recent decades, pharmacometric approaches, such as pharmacokinetic-pharmacodynamic modeling and simulation, are increasingly being applied in the drug development process. The value of these techniques in supporting rational decisions regarding drug use and development is emphasized and ad vocated by the pharmaceutical industry, academia and regulatory agencies [4,1,5–7].
Source: Computer Methods and Programs in Biomedicine - Category: Bioinformatics Authors: Source Type: research