Antifungal Activity of Weed Extracts on < em > Candida Albicans < /em > : An < em > In-vitro < /em > Study

The genusCandidais caused morbidity and mortality in human beings. The virulence factors of theCandida albicanshave the great role in the pseudohyphae formation by attached with epithelial cells and endothelial cells. The aim of the study was to evaluate the antifungal activity of weed extracts used intraditionalherbal medicine. The weeds were selected on the basis of their reported ethnobotanical uses. Water and alcoholic weed extracts were screenedin vitrofor their antifungal activity against fungusC. albicans. 50 μl concentration of minimal Inhibitory Concentration (MIC) ofMimosa pudica extract in alcohol and 70 μl concentration of MIC ofOxalis corniculataextract shows in alcohol. We conclude from this that these extracts exhibit amazing fungicidal properties that support their traditional uses. The presence of phytochemicals in the extracts including, tannins, alkaloids, steroids, glycosides, triterpenoids, flavonoids, phenolic compounds and organic acids like, Malic acid, tartaric acid and citric acid may be responsible for these activities. The acetone extracts of plant are more efficient as compared to the water extract. 

Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Hemalatha Kamurthy Source Type: research