ARCPHdb: a comprehensive protein database for SF1 and SF2 helicase from archaea
Superfamily 1 and Superfamily 2 helicases, two of the largest helicase protein families, play vital roles in many biological processes including replication, transcription and translation. Study of helicase proteins in the model microorganisms of archaea have largely contributed to the understanding of their function, architecture and assembly. Based on a large phylogenomics approach, we have identified and classified all SF1 and SF2 protein families in ninety five sequenced archaea genomes. Here we developed an online webserver linked to a specialized protein database named ARCPHdb to provide access for SF1 and SF2 helicase families from archaea.
Source: Computers in Biology and Medicine - Category: Bioinformatics Authors: Mirna Moukhtar, Wafi Chaar, Ziad Abdel-Razzak, Mohamad Khalil, Samir Taha, Hala Chamieh Source Type: research