Effects of the serotonin transporter gene, sensitivity of response to alcohol, and parental monitoring on risk for problem alcohol use

The serotonin transporter-linked polymorphic region (5-HTTLPR) of the serotonin transporter gene (SLC6A4) has been previously associated with alcohol-related risk. Most findings point to short (S) allele carriers being at increased risk for negative alcohol outcomes relative to long allele homozygotes, although some work indicates a more complex relationship. The current prospective study aimed to clarify how and under what circumstances variations in 5-HTTLPR transmit risk for various alcohol-related outcomes.

Source: Alcohol - December 4, 2016 Category: Addiction Authors: Lora M. Cope, Emily C. Munier, Elisa M. Trucco, Jillian E. Hardee, Margit Burmeister, Robert A. Zucker, Mary M. Heitzeg Source Type: research