Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer
The genome is under constant assault from a multitude of sources that can lead to the formation of DNA double-stand breaks (DSBs). DSBs are cytotoxic lesions, which if left unrepaired could lead to genomic ins...
Source: Clinical and Translational Medicine - Category: Internal Medicine Authors: Sonali Bhattacharjee and Saikat Nandi Source Type: research