Modulation of Urinary Siderophores by the Diet, Gut Microbiota and Inflammation in Mice

In this study, we have employed Chrome Azurol S (CAS) assay which is a well-established method for bacterial siderophores study, to detect and quantify mammalian siderophores in urine samples. Our study demonstrates that siderophores in urine can be altered by diet, gut microbiota and inflammation. C57BL/6 mice, fed on plant-based chow diets which contain numerous phytochemicals, have more siderophores in the urine compared to those fed on purified diets.

Source: The Journal of Nutritional Biochemistry - December 1, 2016 Category: Biochemistry Authors: Xia Xiao, Beng San Yeoh, Piu Saha, Yuan Tian, Vishal Singh, Andrew D. Patterson, Matam Vijay-Kumar Source Type: research