The Landscape of Cutaneous Lymphomas in 2016, an Introduction

The approach to the classification of cutaneous lymphomas has been challenged by the competing demands of an “organ-specific” approach vs. a desire to better understand common features of lymphomas affecting multiple anatomic sites1,2. For example, some lymphoma subtypes that may present in the skin as well as other anatomic sites, such as extranodal marginal zone lymphoma, share some histological and immunophenotypic features, but still differ in underlying biology and clinical behavior. Conversely, some lymphomas presenting primarily in the skin, such as adult T-cell leukemia/ lymphoma or intravascular large B-cell lymphoma may represent manifestations of systemic disease.

Source: Seminars in Diagnostic Pathology - December 1, 2016 Category: Pathology Authors: Alejandro A Gru, Elaine S. Jaffe Source Type: research