Studying CA-125 tumor marker level in different stages, histopathological types, and grades of endometrial cancer

Objective: The aim of this study was to correlate the level of CA125 in different stages, histopathological types, and grades of endometrial cancer. Patients and methods: Prospective study was conducted on 120 endometrial cancer patients who underwent full surgical staging, preoperative measurement of CA125, histopathological examination, and grading of uterus and pelvic lymph nodes. Results: Histopathology of the cases revealed the following: 102 cases were endometrioid adenocarcinoma, 17 cases were serous papillary adenocarcinoma, and one case was clear cell carcinoma. All 25 (100%) cases with advanced-stage disease had a CA-125 level of at least 35 U\ml, compared with 52 of 95 (54.7%) cases with early-stage disease (P
Source: Journal of Evidence-Based Women’s Health Journal Society - Category: OBGYN Tags: Original articles Source Type: research