Serum cortisol of Sahel goats following rumenotomy with assorted anaesthetics and sutures

Publication date: Available online 30 November 2016 Source:International Journal of Veterinary Science and Medicine Author(s): Abubakar Mshelia Saidu, Paul B. Bokko, Abdullahi Mohammed, David N. Bukbuk, Ephraim Igwenagu The utmost need for pragmatic combination of surgical sutures and local anaesthetic that would evoke minimal post-surgical stress response and allow uncomplicated healing is essential for successful surgeries. Fifteen Sahel goats were randomly allocated into three groups A, B and C to quantitatively assay (ELISA) serum cortisol profiles following rumenotomy, as markers of surgical stress. Diazepam at 0.2mg/kg was administered intravenously to groups A and B with subsequent lidocaine HCl and bupivacaine inverted-L block respectively. Group C did not receive any treatment. Chromic catgut (CCG) and polyglycolic acid (PGA) sutures were used for rumen and abdominal muscles closure for groups A and B respectively and nylon for skin closure. Blood sampling were at post anaesthetic induction (PAI) and post-surgery at 0, 5, 8, 24, 48 and 72h. The Group A goats expressed serum cortisol that was significantly high 52.76±6.12ng/mL at 5h post-surgery. At 8h post-surgery serum cortisol for both groups A (72.53±3.79ng/mL) and B (61.59±3.90ng/mL) were at their peak. Serum cortisol levels compared to the baseline data were significantly different (P <0.05) at 5, 24, and 48h for the CCG goats. The serum cortisol levels at 72h drastically decreased to 20.53±8.7...
Source: International Journal of Veterinary Science and Medicine - Category: Veterinary Research Source Type: research