Sleep Homeostatic and Waking Behavioral Phenotypes in Egr3-Deficient Mice Associated with Serotonin Receptor 5-HT2 Deficits

Conclusion:Egr3 has an essential role in regulating cortical arousal, wakefulness, and sleep, presumably by its regulation of 5-HT2 receptors.Citation:Grønli J, Clegern WC, Schmidt MA, Nemri RS, Rempe MJ, Gallitano AL, Wisor JP. Sleep homeostatic and waking behavioral phenotypes inEgr3-deficient mice associated with serotonin receptor 5-HT2 deficits.SLEEP 2016;39(12):2189–2199.
Source: Sleep - Category: Sleep Medicine Source Type: research