Reduced Rapid Eye Movement Density in Parkinson Disease: A Polysomnography-Based Case-Control Study

Conclusions:REM density is reduced in patients with IPD and correlates with subjective scores on sleep impairment. As an indicator of persistent high sleep pressure, reduced RD in IPD is eligible as a biomarker of excessive daytime sleepiness in IPD. It possibly reflects direct involvement of the brainstem REM generation sites by the disease process. RD is a promising new tool for sleep research in IPD.Citation:Schroeder LA, Rufra O, Sauvageot N, Fays F, Pieri V, Diederich NJ. Reduced rapid eye movement density in parkinson disease: a polysomnography-based case-control study.SLEEP 2016;39(12):2133–2139.
Source: Sleep - Category: Sleep Medicine Source Type: research