TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization

We present TopPIC, a tool that efficiently identifies and characterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutations and post-translational modifications, by searching top-down tandem mass spectra against a protein database. Availability and Implementation: http://proteomics.informatics.iupui.edu/software/toppic/ Contact: xwliu@iupui.edu Supplementary information: Supplementary data are available at Bioinformatics online.
Source: Bioinformatics - Category: Bioinformatics Authors: Tags: SEQUENCE ANALYSIS Source Type: research