Remodelling germ cells by intercellular cannibalism

Nature Cell Biology 18, 1267 (2016).
doi:10.1038/ncb3449

Authors: Jennifer K. Heppert & Bob Goldstein
Work from the early 1980s reported strange lobes protruding from Caenorhabditis elegans germ cell precursors. However, the fate and potential significance of these lobes remained unexplored for decades. Now, neighbouring endodermal cells are shown to sever and digest these lobes, in an unexpected process of 'intercellular cannibalism', which could play an important part in regulating primordial germ cells.

Source: Nature Cell Biology - November 28, 2016 Category: Cytology Authors: Jennifer K. Heppert Bob Goldstein Tags: News and Views Source Type: research