Association between insulin resistance and serum and salivary irisin levels in patients with psoriasis vulgaris

Conclusion This is the first study evaluating irisin levels in patients with psoriasis vulgaris in the literature. The results of our study show that serum and salivary irisin levels were significantly lower in the patient group when compared with the control group. Irisin levels in patients with severe psoriasis were low, suggesting that irisin may have a role in the pathogenesis of psoriasis and may be a marker showing the severity of psoriasis, which could warn us against the development of insulin resistance and diabetes mellitus.
Source: Dermatologica Sinica - Category: Dermatology Source Type: research