Poor sleep quality related to worse vascular function in individuals with multiple sclerosis
Background: Poor sleep quality has been related to poor vascular function and higher risk of cardiovascular disease in the general population. Persons with multiple sclerosis (MS) exhibit a high cardiovascular risk, and report poor sleep quality. To date, the association between sleep quality and vascular health in MS has not been investigated. Objective: To investigate differences in vascular health between good and poor quality sleepers with MS. Methods: After a 10 minute rest in the supine position, resting heart rate (HR) and brachial blood pressure (BP) were collected.Aortic SBP, augmentation index (AIX), HR normalized AIX (AIX@HR75), subendocardial viability ratio (SEVR), end systolic pressure (ESP), and central pulse wave velocity (PWVc) were measured with applanation tonometry in individuals with MS (n=49).
Source: Artery Research - Category: Cardiology Authors: Thessa Hilgenkamp, Garett Griffith, Robert Motl, Tracy Baynard, Bo Fernhall Source Type: research
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