Effects on vascular structure and function of single at1r blockade or its combination with CCB, diuretics or their triple association

Environment/Objectives: The antihypertensive efficacy of Valsartan (VAL) is largely known in monotherapy and combination with CCB and diuretics (D) but there is scarce evidence of its vascular effects in subjects younger than 60 y.o. Otherwise, there is a rationale supporting using combinations in high CV risk or patients with higher BP but vascular findings are not considered still as a reason.

Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Pedro Forcada, Carlos Castellaro, Jorge Chiabaut, Sergio Gonzalez, Carol Kotliar, Sebastian Obregon Source Type: research