Preface to a special issue on genetic models of alcoholism and alcohol-stress interactions

This special issue of Alcohol brings together papers on mouse models of human alcohol use and abuse. Many of the papers have themes at the interface between alcoholism and the neurobiology of stress. Many are from members of the Integrative Neuroscience Initiative on Alcoholism (INIA) consortium —a large collaboration initiated by the National Institute on Alcohol Abuse and Alcoholism in 2002. These papers address some of the following questions: (1) What are the causal and mechanistic links between stressors and subsequent risk of alcoholism? (2) What genes, gene variants, and mechanisms account for highly variable responses to alcohol? (3) What are the long-lasting molecular effects of stress and alcohol abuse on the CNS? (4) Can we devise treatments to reduce the allostatic burden of alcoholism?
Source: Alcohol - Category: Addiction Authors: Source Type: research