Tumour metabolism: RED(D1) or dead

Nature Reviews Cancer 16, 754 (2016). doi:10.1038/nrc.2016.132 Author: Nicola McCarthy Mathias Wenes and colleagues have studied metabolic changes in tumour associated macrophages (TAMs) and found that specific alterations of mTOR regulation through regulated in development and DNA damage response 1 (REDD1) results in defective blood vessel formation and increased metastasis.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research