Tumour metabolism: RED(D1) or dead
Nature Reviews Cancer 16, 754 (2016).
doi:10.1038/nrc.2016.132
Author: Nicola McCarthy
Mathias Wenes and colleagues have studied metabolic changes in tumour associated macrophages (TAMs) and found that specific alterations of mTOR regulation through regulated in development and DNA damage response 1 (REDD1) results in defective blood vessel formation and increased metastasis.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Nicola McCarthy Tags: Research Highlight Source Type: research
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