Cytokine signatures in hereditary fever syndromes (HFS)

Autoinflammatory disorders (AIDs) are a group of inherited diseases characterized by unprovoked episodes of systemic inflammation. These disorders differ from autoimmune diseases as their pathogenesis is not mediated by self-reactive antibodies or T lymphocytes [1]. Another distinction between these two groups of disorders is the primary role of the innate immune system in mediating autoinflammatory diseases, versus the recognized importance of the adaptive immune system in autoimmune disorders [2].
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Source Type: research