Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors

Nature Reviews Molecular Cell Biology 17, 783 (2016). doi:10.1038/nrm.2016.122 Authors: Ellis R. Levin & Stephen R. Hammes Steroid hormone receptors mediate numerous crucial biological processes and are classically thought to function as transcriptional regulators in the nucleus. However, it has been known for more than 50 years that steroids evoke rapid responses in many organs that cannot be explained by gene regulation.
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research