Regulation of disease-associated gene expression in the 3D genome
Nature Reviews Molecular Cell Biology 17, 771 (2016).
doi:10.1038/nrm.2016.138
Authors: Peter Hugo Lodewijk Krijger & Wouter de Laat
Genetic variation associated with disease often appears in non-coding parts of the genome. Understanding the mechanisms by which this phenomenon leads to disease is necessary to translate results from genetic association studies to the clinic. Assigning function to this type of variation is notoriously difficult
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Peter Hugo Lodewijk Krijger Wouter de Laat Tags: Review Source Type: research