Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression

Nature Reviews Molecular Cell Biology 17, 756 (2016). doi:10.1038/nrm.2016.126 Authors: Jesse M. Engreitz, Noah Ollikainen & Mitchell Guttman Over the past decade, it has become clear that mammalian genomes encode thousands of long non-coding RNAs (lncRNAs), many of which are now implicated in diverse biological processes. Recent work studying the molecular mechanisms of several key examples — including Xist, which orchestrates X chromosome
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research