Genome-wide mapping and analysis of chromosome architecture

Nature Reviews Molecular Cell Biology 17, 743 (2016). doi:10.1038/nrm.2016.104 Authors: Anthony D. Schmitt, Ming Hu & Bing Ren Chromosomes of eukaryotes adopt highly dynamic and complex hierarchical structures in the nucleus. The three-dimensional (3D) organization of chromosomes profoundly affects DNA replication, transcription and the repair of DNA damage. Thus, a thorough understanding of nuclear architecture is fundamental to the study of nuclear processes
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research