Mapping the 3D genome: Aiming for consilience
Nature Reviews Molecular Cell Biology 17, 741 (2016).
doi:10.1038/nrm.2016.151
Author: Job Dekker
The spatial organization of genomes is studied using microscopy- and chromosome conformation capture (3C)-based methods. The two types of methods produce data that are often consistent, but there are cases where they appear discordant. These cases provide opportunities to derive better models of chromatin folding,
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Job Dekker Tags: Comment Source Type: research