Cell Senescence: Controlling the senescence-associated secretory phenotype

Nature Reviews Molecular Cell Biology 17, 740 (2016). doi:10.1038/nrm.2016.157 Author: Paulina Strzyz Cell entry into senescence is typically irreversible and is associated with heterochromatization of the genome, which is marked by the establishment of senescence-associated heterochromatin foci (SAHF). However, in contrast to many genes that are silenced on senescence entry (including pro-proliferative genes), the expression of factors
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research