Palifermin and Chlorhexidine Mouthwashes in Prevention of Chemotherapy-Induced Mucositis in Children with Acute Lymphocytic Leukemia: a Randomized Controlled Trial

Conclusion:Palifermin reduces the oral mucositis in children with ALL. Several mechanisms of action are suggested for keratinocyte growth factor (such as palifermin) including promotion of cell proliferation and cytoprotection, restraining the apoptosis, and changing the cytokine profile.Keywords  ●Oral Mucositis  ●Palifermin  ●Leukemia 
Source: Journal of Dentistry, Shiraz University of Medical Sciences - Category: Dentistry Source Type: research