High versus Low Blood-Pressure Target in Patients with Septic Shock

This multicentre, open label trial randomized over 700 patients with septic shock to undergo resuscitation to MAP target of 80-85 mmHg or 65-70 mmHg. The primary outcome of mortality was no different in either group at 28 or 90 days. However, the higher target group required less renal replacement therapy. : Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care. Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Acute Kidney Injury Clinical Nephrology Clinical Trial Results General Nephrology Source Type: research