AURA-LV: Successful Treatment of Active Lupus Nephritis with Voclosporin

ASN 2016 High Impact Clinical Trial William Franklin Pendergraft, James A. Tumlin, Brad H. Rovin, Mary Anne Dooley, David R.W. Jayne, David Wofsy, Frederic A. Houssiau, David Isenberg, Tak Mao Chan, Neil Solomons, Robert B. Huizinga In patients with biopsy proven lupus nephritis, complete remission at 24 weeks was reached by 32.6% (p = 0.045) in low dose voclosporin arm, compared to 27.3%(p=0.204) in the high-dose arm and 19.3% in control arm.  Voclosporin was used in combination with MMF and corticosteroids. : The PROMISE Study: A Phase 2b Multicenter Study of Voclosporin (ISA247) Versus Tacrolimus in De Novo Kidney Transplantation Comparison of low-dose intravenous cyclophosphamide with oral mycophenolate mofetil in the treatment of lupus nephritis Everolimus with Very Low-Exposure Cyclosporine A in De Novo Kidney Transplantation: A Multicenter, Randomized, Controlled Trial
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Clinical Trial Results Conference Alert Source Type: research