Polyphenol-enriched Vaccinium uliginosum L. fractions reduce retinal damage induced by blue light in A2E-laden ARPE19 cell cultures and mice

Polyphenols exert beneficial effects on vision. We hypothesized that polyphenol components of Vaccinium uliginosum L (V.U.) extract protect retina pigment epithelial (RPE) cells against blue light-induced damage. Our aim was to test extracts containing polyphenol components to ascertain effects to reduce damage against blue light in RPEs. We measured the activity in fractions eluted from water (VE), ethanol (FE), and HP20 resin (FH), and found that the FH fraction had the highest beneficial activity.

Source: Nutrition Research - November 17, 2016 Category: Nutrition Authors: Bom-Lee Lee, Jung-Hwan Kang, Hye-Mi Kim, Se-Hee Jeong, Dae-Sik Jang, Young-Pyo Jang, Se-Young Choung Tags: Original Research Source Type: research