Cisplatin-related Cerebral Infarction in Testicular Germ Cell Cancer: Short Report of Three Cases and Pathomechanism

Cisplatin-based combination therapy leads to high remission rates in germ cell cancer (GCC). Therefore, acute and chronic complications as consequences of cisplatin vascular toxicity are of special interest as they potentially contribute to significantly increased morbidity and mortality. Cerebrovascular accidents associated with cisplatin therapy in GCC patients have been occasionally described in the literature [1]. The majorities of GCC patients are young and have few or no vascular risk factors (VRF).
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Tags: Case Report Source Type: research