A novel method for assessing chronic cortisol concentrations in dogs using the nail as a source

Cortisol, a glucocorticoid secreted in response to stress is used to assess adrenal function and mental health in clinical settings. Current methods assess cortisol sources that reflect short-term secretion that can vary with current stress state. Here we present a novel method for the extraction and quantification of cortisol from the dog nail using solid phase extraction coupled to enzyme-linked immunosorbent assay. Validation experiments demonstrated accuracy (r = 0.836, P

Source: Domestic Animal Endocrinology - November 16, 2016 Category: Endocrinology Authors: Z. Mack, H.B. Fokidis Source Type: research